ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FAIM2
Symbol Alias	KIAA0950, LFG, NMP35, LIFEGUARD, TMBIM2, LFG2
Approved Name	Fas apoptotic inhibitory molecule 2
Name Alias	"transmembrane BAX inhibitor motif containing 2"
Location	12q13
Position	chr12:50260679-50298000, -1
External Links	HGNC: 17067 Entrez Gene: 23017 Ensembl: ENSG00000135472 UCSC: uc001rvj.2
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin; Mapped by LD-proxy

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Albayrak O., 2013	No significant association was reported in this study.	Non-significant

Gene related SNPs (count: 3)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs7138803	chr12:50247468(Fwd)		1(0/1/0)

rs_ID	Location	Functional Annotation
rs297924	chr12:50285061(Fwd)	intron_variant; NMD_transcript_variant
rs7132908	chr12:50263148(Fwd)	3_prime_UTR_variant; downstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030054	cell junction	cellular component	IEA	84
GO:0045211	postsynaptic membrane	cellular component	IEA	45
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0045121	membrane raft	cellular component	IDA[17635665]	24
GO:0043066	negative regulation of apoptotic process	biological process	NAS[10535980]	85
GO:0006915	apoptotic process	biological process	IEA	127
GO:0005575	cellular_component	cellular component	ND	118
GO:0021680	cerebellar Purkinje cell layer development	biological process	ISS	3
GO:0021702	cerebellar Purkinje cell differentiation	biological process	ISS	4
GO:0043523	regulation of neuron apoptotic process	biological process	IMP[17635665]	4
GO:0021549	cerebellum development	biological process	ISS	5
GO:0021681	cerebellar granular layer development	biological process	ISS	1
GO:0005886	plasma membrane	cellular component	IEA	839

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FAIM2 (count: 0)

Genes shared at least 2 KEGG pathways with FAIM2 (count: 0)

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Region: chr12:50260679..50298000 View in gBrowse