ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CIRBP
Symbol Alias	CIRP
Approved Name	cold inducible RNA binding protein
Previous Name	"cold inducible RNA-binding protein"
Name Alias	"Cold-inducible RNA-binding protein", "glycine-rich RNA binding protein"
Location	19p13.3
Position	chr19:1259384-1274879, 1
External Links	HGNC: 1982 Entrez Gene: 1153 Ensembl: ENSG00000099622 UCSC: uc002lrr.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Ramos[2014]_4	chr19:1083637-1222274 (NCBI Build 36.1 (hg18))	0		Duplication

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0009411	response to UV	biological process	IDA[11574538]	8
GO:0005737	cytoplasm	cellular component	IDA[11574538]; ISS	781
GO:0030371	translation repressor activity	molecular function	ISS	1
GO:0017148	negative regulation of translation	biological process	ISS	6
GO:0003730	mRNA 3'-UTR binding	molecular function	IDA[16513844]	10
GO:0005654	nucleoplasm	cellular component	IEA	210
GO:0048255	mRNA stabilization	biological process	IDA[11574538]	5
GO:0045727	positive regulation of translation	biological process	IDA[11574538]	6
GO:0005634	nucleus	cellular component	IDA[11574538]; ISS	877
GO:0070181	SSU rRNA binding	molecular function	IDA[11574538]	1
GO:0005515	protein binding	molecular function	IPI[16513844]	1015
GO:0034063	stress granule assembly	biological process	ISS	3
GO:0009409	response to cold	biological process	TAS[9151692]	9
GO:0010494	cytoplasmic stress granule	cellular component	ISS	6
GO:0000166	nucleotide binding	molecular function	IEA	83

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CIRBP (count: 11)

Gene Symbol	Pathway Count	Pathway List
RBM4	8	cytoplasm; negative regulation of translation; mRNA 3'-UTR binding; nucleoplasm; nucleus; protein binding; cytoplasmic stress granule; nucleotide binding;
IGF2BP3	6	cytoplasm; negative regulation of translation; mRNA 3'-UTR binding; nucleus; protein binding; nucleotide binding;
RNPS1	6	cytoplasm; mRNA 3'-UTR binding; nucleoplasm; nucleus; protein binding; nucleotide binding;
XPA	5	response to UV; nucleoplasm; nucleus; protein binding; nucleotide binding;
MEN1	5	response to UV; cytoplasm; nucleoplasm; nucleus; protein binding;
PARN	5	cytoplasm; mRNA 3'-UTR binding; nucleus; protein binding; nucleotide binding;
FUS	5	cytoplasm; nucleoplasm; nucleus; protein binding; nucleotide binding;
ATXN2	5	cytoplasm; nucleus; protein binding; stress granule assembly; cytoplasmic stress granule;
HNRNPH1	5	cytoplasm; nucleoplasm; nucleus; protein binding; nucleotide binding;
HNRNPA2B1	5	cytoplasm; nucleoplasm; nucleus; protein binding; nucleotide binding;
MAPK1	5	cytoplasm; nucleoplasm; positive regulation of translation; nucleus; protein binding;

Genes shared at least 2 KEGG pathways with CIRBP (count: 0)

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Region: chr19:1259384..1274879 View in gBrowse